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EDGE PLUS Method: How to Lose Weight Quickly and in a Controlled Medical Environment

ketosis metabolim regenmed360 weight loss Apr 22, 2026
EDGE PLUS Method with continuous glucose and ketosis monitoring explained by Dr Octavio Sousa in Panama

For more than 25 years as a physician, I have worked with patients who struggle to lose weight despite trying multiple approaches.

In many cases, the issue is not diet alone, but the fact that the body is operating in a metabolic state that does not support fat loss.

For this reason, I developed the EDGE PLUS Method, a structured medical strategy designed to create a controlled metabolic environment, allowing the body to respond more efficiently.

Why do many people struggle to lose weight?

From a physiological perspective, metabolism can be affected by:

  • Hyperinsulinemia
  • Chronic inflammation
  • Insulin resistance
  • Continuous digestive overload
  • Hormonal imbalances

When these factors are present:

  • At mobilization becomes difficult
  • Energy is stored instead of used
  • Metabolic efficiency decreases

In this context, traditional diets often fail.

The core principle: controlled ketosis

The EDGE PLUS Method is based on a key concept:

Modulating the metabolic environment through medically supervised controlled ketosis over approximately 10–12 days

The goal is not simply calorie restriction, but to create specific physiological conditions that promote:

  • Fat utilization as a primary energy source
  • Hormonal regulation
  • Appetite control
  • Metabolic efficiency

Early ketosis induction within the first 24–48 hours

One of the most relevant aspects of the method is the early induction of ketosis.

Within the first 24 to 48 hours, the body may:

  • Lower insulin levels
  • Shift toward fat as its primary fuel source
  • Increase ketone production

This can lead to:

  • Reduced appetite
  • Improved mental clarity
  • Stable energy levels
  • Initial weight loss

This process occurs within a controlled and supervised metabolic environment.

Continuous metabolic monitoring: precision medicine

A key differentiator of the EDGE PLUS Method is the use of continuous metabolic monitoring technology.

At RegenMed360, we monitor patients over a 24-hour period using tools that allow us to track:

  • Glucose levels
  • Metabolic variability
  • Physiological response
  • ketosis status

This enables us to:

  • Understand each patient’s metabolism in real time
  • Adjust the protocol precisely
  • Optimize results
  • Avoid generic approaches

In other words, treatment decisions are based on real data, not assumptions.

Structure of the EDGE PLUS Method

The method is not a diet, but a structured medical protocol divided into phases.

Phase 1: Metabolic induction (10–12 days)

During this phase, a discreet pediatric-type nasogastric tube is used temporarily to deliver a continuous nutritional formula directly to the stomach.

This formula contains:

  • Essential amino acids
  • Vitamins
  • Minerals

The goal of this phase is to:

  • Induce ketosis
  • Reduce digestive workload
  • stabilize the metabolic environment
  • Facilitate metabolic adaptation

Phase 2: Nutritional transition

After the tube is removed, a personalized nutrition plan is introduced based on the patient’s response.

This phase helps to:

  • Maintain results
  • Re-educate metabolism

Phase 3: Maintenance and education

This phase focuses on long-term sustainability:

  • Nutritional education
  • Lifestyle optimization
  • Medical follow-up

A method designed for real life

The EDGE PLUS Method is designed to be adaptable.

Patients can continue their daily activities:

  • At home
  • At work
  • While traveling

Personalized medical approach

Each protocol is tailored based on:

  • Anthropometric characteristics
  • Clinical diagnosis
  • Metabolic response

The program may also include:

  • Targeted supplementation
  • Ketosis monitoring
  • Continuous medical supervision

What can patients experience?

When properly implemented, patients may experience:

  • Reduced appetite
  • Stable energy levels
  • Weight loss
  • Improved body composition

These effects are driven by metabolic modulation.

More than weight loss: a metabolic reset

The EDGE PLUS Method aims to achieve what can be described as a:

Metabolic reset

This may contribute to improvements in:

  • Insulin resistance
  • Metabolic disorders
  • Blood pressure regulation
  • Overall metabolic health

Always under medical supervision.


Medical supervision is essential

This type of protocol must be applied with:

  • Medical evaluation
  • Clinical supervision
  • Individualized care

Each body responds differently, which is why personalization is critical.

Are you considering this approach?

If you have struggled with weight loss or feel that your metabolism is not responding, it is essential to evaluate your case individually.

At RegenMed360 in Panama, we perform comprehensive assessments to design personalized strategies.

Do you want to improve your metabolism and cellular health?

At RegenMed360, we perform comprehensive evaluations to understand how your metabolism is functioning and design a personalized plan to optimize your health.

Our approach integrates metabolic medicine and regenerative medicine to help you restore your body鈥檚 natural balance.

Book a Consultation

Would you like to better understand how your body works?

Dr. Octavio Sousa explains it in the video below.

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